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PROGRESS IN Nucleic Acid Research Volume 1PDF|Epub|txt|kindle电子书版本网盘下载
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图书目录
“Primer” in DNA Polymerase Reactions F.J.BOLLUM1
Ⅰ.Introduction1
Ⅱ.Definitions and Polymer Principles2
Ⅲ.Priming Activity as a Function of Molecular Weight and State4
Ⅳ.Chemical and Physical Effects as an Aid in Elucidating Mechanism14
Ⅴ.Hypothetical Mechanism for DNA Synthesis19
Ⅵ.Summary24
References25
The Biosynthesis of Ribonucleic Acid in Animal Systems R.M.S.SMELLIE27
Ⅰ.Introduction27
Ⅱ.Systems Incorporating One or Two Ribonucleotides into Polyribonucleotides30
Ⅲ.Systems Incorporating All Four Ribonucleotide Residues37
Ⅳ. Requirement for a Primer41
Ⅴ. Site of RNA Biosynthesis in the Cell46
Ⅵ. Speculations as to the Significance of the Different Synthetic Pathways49
References55
The Role of DNA in RNA Synthesis JERARD HURWITZ AND J.T.AUGUST59
Ⅰ.Introduction59
Ⅱ.The in Vivo Control of RNA Synthesis by DNA59
Ⅲ.The in Vitro Control of RNA Synthesis by DNA62
Ⅳ.Conclusion89
References90
Polynucleotide Phosphorylase M.GRUNBERG-MANAGO93
Ⅰ.Introduction93
Ⅱ.Isolation of Polynucleotide Phosphorylase94
Ⅲ.The Catalytic Reaction99
Ⅳ.Reaction Mechanism111
Ⅴ.Polymers125
Ⅵ.Physiological Function of Polynucleotide Phoephorylase127
References129
Messenger Ribonucleic Acid FRITZ LIPMANN135
Ⅰ.Synopsis135
Ⅱ.Synthesis of Template RNA138
Ⅲ.Kinetics of mRNA Synthesis145
Ⅳ.In Vitro Combination of Ribosomes with Added RNA154
Ⅴ.The Functioning of mRNA in Peptide Synthesis155
Ⅵ.Conclusion157
References158
The Recent Excitement in the Coding Problem F.H.C.CRICK163
Ⅰ.Introduction164
Ⅱ.General Questions168
Ⅲ.The Cell-Free System175
Ⅳ.Amino Acid Changes from a Single Mutation186
Ⅴ.Further Experimental Evidence194
Ⅵ.Is the Code Degenerate?198
Ⅶ.Theoretical Matters203
Ⅷ. General Observations212
Addendum214
References215
Some Thoughts on the Double-Stranded Model of Deoxyribonucleic Acid AARON BENDICH AND HEBBERT S.ROSENKRANZ219
Text219
Concluding Remarks227
Referencon227
Denaturation and Renaturation of Deoxyribonucleic Acid J.MARMUR,R.ROWED,AND C.L.SCHILDKRAUT231
Ⅰ.Properties of the Native and Denatured States of RNA232
Ⅱ.Early Denaturation Studies on DNA235
Ⅲ.Denaturation and Evidence for Strand Separation240
Ⅳ.General Aspects of Denaturation and Renaturation257
Ⅴ.Mechanism of Renaturation271
Ⅵ.Hybrid Formation278
Ⅶ.Applications of Renaturation288
Ⅷ.Summary291
References293
Some Problems Concerning the Macromolecular Structure of Ribonucleic Acids A.S.SPIRIN301
Ⅰ.Introduction301
Ⅱ. Chain Length303
Ⅲ.Chain Conformation of RNA in Solution315
Ⅳ.On Chain Conformation within Riboeomes338
Ⅴ.Conclusion341
References341
The Structure of DNA as Determined by X-ray Scattering Techniques VITTORIO LUZZATI347
Ⅰ.Introduction347
Ⅱ.X-ray Diffraction Technique348
Ⅲ.The Chemical and Physicochemical Evidence351
Ⅳ.The Structure of DNA Fibers352
Ⅴ.The Strueture of DNA in Solution353
Ⅵ.Discussion and Conclusions363
References366
Molecular Mechanisms of Radiation Effects A.WACKER369
Ⅰ.Preface369
Ⅱ.Ultraviolet Light370
Ⅲ.X-rays395
Ⅳ.Conclusion396
References398
AUTHOR INDEX401
SUBJECT INDEX416